Typhoid vaccine
There are two different forms of the typhoid vaccine: a pill and a shot. Your MinuteClinic® provider can help you decide which form of the vaccine is right for you.
Find care
We offer services at MinuteClinic and CVS Pharmacy®

Insurance and pricing
Most insurance accepted. Check your coverage or estimate the cost of your visit if you’re uninsured or prefer to pay out-of-pocket.
Looking for typhoid vaccine and typhoid fever info? Start here.
What is the typhoid vaccine?
The typhoid vaccine helps protect your body from typhoid fever. Since the disease is rare in the U.S., typhoid vaccines are reserved for those traveling to areas where the disease is more common.
Typhoid vaccines can help to prevent typhoid fever, but they are not 100% effective. Typhoid vaccines also lose effectiveness over time and may require a booster. To help prevent infection and typhoid fever, always practice safe eating and drinking habits.
What is typhoid fever?
Typhoid fever is a serious disease that’s caused by Salmonella typhi bacteria. Most infections happen after contact with contaminated food, water or people who carry the disease.
Typhoid fever is often difficult to treat and can cause life-threatening complications, including brain swelling (encephalitis) and internal bleeding. Even after treatment, some people continue to shed active bacteria (in their urine and feces) that can infect others.
People who get typhoid fever can become very sick with a high fever, weakness, stomach pain and headache. According to the Centers for Disease Control (CDC), about 300 cases of typhoid are diagnosed in the U.S. every year. Most of those cases are travelers who did not take the proper precautions before leaving on their trip.
The good news is there are ways to protect yourself and reduce your risks of getting typhoid fever. Whether traveling for business or pleasure or to visit family and friends, it’s important to be prepared.
Getting help
If you’re planning to travel, a MinuteClinic provider can help determine whether you need to be concerned about typhoid fever. Your MinuteClinic provider can also recommend ways you can avoid this illness, determine if the vaccine is appropriate for you, administer the vaccine and answer any questions you might have.
- You may have to answer a few questions to help us prepare for your visit prior to scheduling your appointment.
- Check-in varies depending on how you scheduled your appointment.
If you made your appointment online:
Check in using the email or text message we sent to confirm your appointment. If you prefer to check in using the electronic kiosk, make sure you have your confirmation code.
If you made your appointment in the clinic:
Sign in at the electronic kiosk.
If you made a MinuteClinic Virtual Care® appointment:
To join your virtual visit, use the link in the email or text message we sent you to confirm your appointment. Please join 15 minutes before your scheduled visit time. You will need your date of birth and zip code to join the visit.
- When it's time for your appointment, a provider will call your name.
- Your provider will conduct a thorough examination based on your reason for visit, presenting symptoms and health history. Charges will be based on examination and services provided during the visit.
- At the end of your visit, you are provided with a visit summary, receipt and educational material about your diagnosis. At your request, we can send your primary care provider information about your visit.
Typhoid vaccine protection and side effects
The Centers for the Disease Control and Prevention (CDC) recommends vaccinating laboratory workers in contact with salmonella typhi bacteria and those in close contact with a person who actively has typhoid. The CDC also recommends typhoid vaccinations for nearly everyone traveling to destinations where the disease is common, including:
- Asia
- Africa
- Caribbean
- Central America
- Middle East
- South America
You should not get this vaccine if you:
- Are currently breastfeeding or pregnant
- Are currently taking antibiotics or anti-malarial medication
- Have a compromised immune system
- Have a history of allergic reaction to the vaccine
- Have any life-threatening allergies
- Have any moderate illness
The possible side effects of the typhoid vaccine are generally mild and usually clear up within 48 hours. After a typhoid vaccine, you may experience a fever of 100°F (37.8ºC) or higher, flu-like symptoms, a headache, itching skin at the injection site or tenderness at the injection site.
Depending on your destination and vaccine history, your provider may also recommend a travel consultation (additional charges apply) with vaccinations for:
- Chickenpox (varicella)
- Influenza
- Hepatitis A
- Hepatitis B
- Meningococcal disease
- Td (tetanus, diphtheria) or Tdap (tetanus, diphtheria and pertussis)
Typhoid fever causes
Typhoid fever is caused by a type of Salmonella bacteria. It’s similar to the Salmonella that sometimes cause food recalls but is more dangerous. Typhoid bacteria are commonly found in contaminated drinking water and in food in areas with poor sanitation. The infection can be prevented by drinking filtered or bottled water, avoiding certain foods and washing carefully after using the toilet. Common sources of typhoid bacteria include:
- Condiments
- Food from street vendors
- Fountain drinks
- Ice
- Raw or soft-cooked eggs, meat and fish
- Room temperature food
- Salad
- Tap Water
- Unpasteurized dairy products
- Unwashed fruit and vegetables
- Well water
Typhoid fever treatment and prevention
Typhoid fever can be treated with antibiotics. However, antibiotics do not always work because some typhoid bacteria have become resistant to them. This is why getting the vaccine is important. MinuteClinic® providers do not treat typhoid fever cases.
Like all vaccines, there’s a chance that you will get typhoid fever even if you get vaccinated. The vaccine lowers your chances of getting typhoid fever. It also decreases the severity of the disease if you do get it and makes it easier to treat.
IMPORTANT! PLEASE READ: This material is for reference only and should not be used to determine treatment for specific medical conditions. Please visit a health care provider for evaluation, diagnosis and treatment of any symptoms you may be experiencing. If you're experiencing a medical emergency, please dial 911 or visit your local emergency department.
REFERENCES USED AS SOURCES FOR THIS PAGE:
-
1Typhoid Fever | Disease Directory | Travelers’ Health via CDC. Accessed: 28 August 2024.
-
2Typhoid Fever via WHO. Accessed: 28 August 2024.
-
3Global Typhoid Fever Vaccination via Mayo Clinic. Accessed: 28 August 2024.
-
4Typhoid Fact Sheet via WHO. Accessed: 28 August 2024.
-
5Typhoid Vaccine - What You Need to Know via Drugs.com. Accessed: 28 August 2024.
-
6Typhoid Vaccine, Inactivated Side Effects: Common, Severe, Long Term via Drugs.com Accessed: 28 August 2024.
-
7Vaccination & Immunoprophylaxis: General Recommendations - Chapter 2 - 2020 Yellow Book | Travelers’ Health via CDC. Accessed: 28 August 2024.