Get Your Flu Shot in Sioux Falls, SD

2024-2025 flu shot season has ended
CVS can still help you and your family stay protected with 14+ vaccinations* available to eligible patients.
Schedule your flu shot and skip the line*
Book an appointment today and avoid the walk-in wait.
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Sioux Falls Flu Shots

Select a store from the list below or view search results for Sioux Falls, SD
CVS Pharmacy

1021 S HIGHLINE PL
SIOUX FALLS, SD, 57110

CVS Pharmacy

3600 S LOUISE AVE
SIOUX FALLS, SD, 57106

Flu shots are available beginning in mid-August at CVS Pharmacy locations in Sioux Falls.

Schedule your flu vaccine appointment online or through the CVS Pharmacy app. You can also call your Sioux Falls CVS Pharmacy or call 1-800-SHOP CVS 1-800-746-7287 (TTY:711). Walk-in flu shot appointments may also be available.

*FOR VACCINES OFFERED: Availability varies by state based on regulations. This is not an all-inclusive list of who should be vaccinated. Age restrictions apply. Available when a certified immunizer is on duty.